First of all thanks to every one who takes the time to reply to the questions and share there knowlage and opinitions. I've been a member for about 6 months but this is my first post. At a steady throttle position starting at aprox 2500 rpm's and above the bike starts runnng rough like a richly jetted two stroke,(daa-da-da-daa). The problem happens both under load and while sitting with the bike in gear so the rev limiter would not be a factor. I have been through the entire jetting spectrum from extremly lean (1 3/4 P.S,42 P.J,3rd clip position, 140 main) to way fat (3 1/2 P.S,50 P.J,5th clip position yz needle, 170main) i have tried different blends of fuel from 92 pump fuel to 114 canned fuel, different custom exhaust tips from varing degees of restriction, gray wire plugged in,un-plugged, air box baffle in,out. i have had the Yama band aid for the woodruff key performed(didn't need it, valves checked, TPS and coil checked and it still runs rough. The bike is an 03 450 but if any of the previous years have had a problem like this or if any of you fellow TTrs see an area I may be over looking please reply. What little hair and patience that i still have i would like to save(I have teen age daughters). Thanks in advance.