I'm a mechanical engineer and remember crossing this bridge when studying materials science.
If you really want to look into it then check out http://en.wikipedia....vanic_corrosion
My rule of thumb is anti seize on anything with threads, thread locker on things that can't afford to come loose, grease on things that need to move
Depending on what materials you are threading into each other, you need to use the right anti seize or you could be in for a surprise next time you try loosen the bolt
From experience, if you hear a 'cracking sound' when loosening a fastener...then you should have probably used anti seize and now is a good time to start
One of the many reasons anti seize is better than plain grease is the fact that it is designed to have a very low coefficient of friction, which does not effect the torque setting as much.
Its probably highly likely that the torque setting was specified with anti seize present anyway.
Some issues with anti-seize products may arise from improper application.
To correctly apply an anti-seize product the following parts must be covered in order to protect both metals:
- under the head of the bolt
- the plain part of the bolt
- the thread
- the face and both sides of the nut
- all parts of the washer (if one is used)
By covering all these areas there is no opportunity for metal-on-metal contact and this therefore eliminates the risk of seizing.
Essentially there should be a film of anti-seize between every surface to surface contact.